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Search Results for " Apoptosis inhibitor 4 "

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127

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T8794	4-MMPB	15-Lipoxygenase Inhibitor 1	Apoptosis , Others , Lipoxygenase
	15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxyg...		Apoptosis , Others , Lipoxygenase
T11947	MARK4 inhibitor 1		Apoptosis , Others , AMPK
	MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.		Apoptosis , Others , AMPK
T21679	4'-bromo-Resveratrol		Sirtuin
	4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)		Sirtuin
T6967	RHPS4	RHPS 4 methosulfate,NSC714187	Apoptosis , Telomerase
	RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.		Apoptosis , Telomerase
T22424	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea		Apoptosis , STAT
	SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular ca...		Apoptosis , STAT
T12454	PI-273		Apoptosis , PI4K
	PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells		Apoptosis , PI4K
T3572	NSC 15364	1,3-Bis(4-aminophenyl)urea,NSC15364	Apoptosis , Others , VDAC
	NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.		Apoptosis , Others , VDAC
T8006	Oncrasin-1		Apoptosis , Raf , Ras
	Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations		Apoptosis , Raf , Ras
T1535	Sodium 4-phenylbutyrate	Sodium Phenylbutyrate,Buphenyl,TriButyrate	Apoptosis , HDAC , Autophagy
	Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II histone deacetylases (HDACs )resulting in a global increase in gene expression, decreased cellular proliferation, inc...		Apoptosis , HDAC , Autophagy
T0314	Hexylresorcinol	4-Hexylresorcinol	Apoptosis , Tyrosinase , Antibacterial , Parasite
	Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.		Apoptosis , Tyrosinase , Antibacterial , Parasite
T0125	Epirubicin hydrochloride	Pharmorubicin,4'-epidoxorubicin HCl,Epirubicin HCl,4'-Epidoxorubicin hydrochloride	Apoptosis , DNA/RNA Synthesis , Topoisomerase
	Epirubicin hydrochloride (Pharmorubicin) is an antineoplastic agent which can inhibit Topoisomerase.		Apoptosis , DNA/RNA Synthesis , Topoisomerase
T23450	TCS PrP Inhibitor 13	5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One	Others
	TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.		Others
T6759	AP-III-a4	ENOblock	Glucokinase
	AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.		Glucokinase
T8978	DD1	3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome
	DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
T9104	TJ191		Apoptosis
	TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.		Apoptosis
T11571	HLY78	4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine	Wnt/beta-catenin
	HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.		Wnt/beta-catenin
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T2275	YK-4-279		Apoptosis , DNA/RNA Synthesis
	YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.		Apoptosis , DNA/RNA Synthesis
T4371	CD437	AHPN,O-Desmethyl Adapalene,Apoptosis Activator VI	Retinoid Receptor , Autophagy
	CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.		Retinoid Receptor , Autophagy
T6731	WYE-354		Apoptosis , PI3K , mTOR , Autophagy
	WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ ...		Apoptosis , PI3K , mTOR , Autophagy
T22553	Adaphostin	1-Adamantyl 4-((2,5-Dihydroxybenzyl)Amino)Benzoate,NSC 680410	Bcr-Abl
	Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.		Bcr-Abl
T6659	SB 415286	SB415286	Apoptosis , GSK-3
	SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.		Apoptosis , GSK-3
T2258	VER-50589	VER50589	Apoptosis , HSP
	VER-50589 is a potent HSP90 inhibitor.		Apoptosis , HSP
T8505	SC-236	Sc 236	Apoptosis , COX , PPAR
	SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).		Apoptosis , COX , PPAR
T6481	Droxinostat	NS 41080	Apoptosis , HDAC
	Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.		Apoptosis , HDAC
T7644	DPN	Diarylpropionitrile	Apoptosis , Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Autophagy
	DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .
T6603	Nelarabine	GW 506U78,Nelzarabine,506U78	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
T6525	GW 5074	GW5074,Raf1 Kinase Inhibitor I	Apoptosis , Raf
	GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms.		Apoptosis , Raf
T6440	CGP 57380	MNK1 Inhibitor	Apoptosis , MNK
	CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.		Apoptosis , MNK
T6611	NSC697923	2-[(4-methylphenyl)sulfonyl]-5-nitrofuran	E1/E2/E3 Enzyme
	NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct me...		E1/E2/E3 Enzyme
T0223	Tetrahydroxyquinone	4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone	Apoptosis , Antioxidant , Reactive Oxygen Species
	Tetrahydroxyquinone (Tetroquinone) is a molecule best known as a primitive anticataract drug, is also a highly redox active molecule that can take part in a redox cycle with semiquinone radicals, leading to the formation...		Apoptosis , Antioxidant , Reactive Oxygen Species
T6325	PCI-34051	PCI 34051	Apoptosis , HDAC
	PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).		Apoptosis , HDAC
T8931L	ICCB-19 hydrochloride	ICCB-19 HCl（750621-52-4 free base）	Apoptosis , Others , Autophagy , RIP kinase
	ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal dom...		Apoptosis , Others , Autophagy , RIP kinase
T3100	GSK-J4	GSK J4 HCl	Apoptosis , Histone Demethylase
	GSK-J4 (GSK J4 HCl) is a potent H3K27me3 demethylase inhibitor, with IC50s of 8.6 μM and 6.6 μM towards KDM6B and KDM6A respectively. It is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX wit...		Apoptosis , Histone Demethylase
T9150	SCR130	1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-	Apoptosis , Others , DNA/RNA Synthesis
	SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) is enzyme inhibition, antiproliferative effects and antifungal activity.		Apoptosis , Others , DNA/RNA Synthesis
T15576	Indibulin	ZIO 301,D 24851	Apoptosis , Microtubule Associated
	Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neu...		Apoptosis , Microtubule Associated
T2246	LRRK2-IN-1		Apoptosis , LRRK2 , CDK
	LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.		Apoptosis , LRRK2 , CDK
T12412L	PDK4-IN-1 hydrochloride		Apoptosis , PDK
			Apoptosis , PDK
T2923	Apremilast	CC-10004	Apoptosis , TNF , PDE
	Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.		Apoptosis , TNF , PDE
T9373	DCH36_06	(5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione	Apoptosis , Epigenetic Reader Domain , Histone Acetyltransferase
	DCH36_06 ((5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) as a bona fide is a potent p300/CBP inhibitor
T5045	GSK4112	1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452	Autophagy
	GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.		Autophagy
T6563	LDC000067	LDC067	Apoptosis , CDK
	LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.		Apoptosis , CDK
T2251	NVP-TAE 684	TAE684	Apoptosis , ALK
	NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).		Apoptosis , ALK
T9003	CVT-11127		Dehydrogenase
	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.		Dehydrogenase
T22456	Voreloxin hydrochloride	SNS-595 hydrochloride,Vosaroxin	Apoptosis , Topoisomerase
	Voreloxin hydrochloride (SNS-595 hydrochloride) is a potent inhibitor of Topoisomerase II with broad-spectrum anti-tumor activity.		Apoptosis , Topoisomerase
T6173	BI 2536		Apoptosis , Epigenetic Reader Domain , PLK
	BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.		Apoptosis , Epigenetic Reader Domain , PLK
T2170	SKF-96365 hydrochloride	SKF96365	Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy
	SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha...
T2243	Serdemetan	JNJ-26854165	Apoptosis , Mdm2 , E1/E2/E3 Enzyme , p53
	Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.		Apoptosis , Mdm2 , E1/E2/E3 Enzyme , p53
T1725	Y-27632 dihydrochloride	Y-27632 2HCl	ROCK , Apoptosis
	Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.		ROCK , Apoptosis
T6690	T0901317		Apoptosis , FXR , Liver X Receptor , ROR
	T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).		Apoptosis , FXR , Liver X Receptor , ROR

Compounds

4-MMPB

T8794

Synonym: 15-Lipoxygenase Inhibitor 1

Target: Apoptosis, Others, Lipoxygenase

MARK4 inhibitor 1

T11947

Synonym:

Target: Apoptosis, Others, AMPK

Synonym: RHPS 4 methosulfate,NSC714187

Target: Apoptosis, Telomerase

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

T22424

Synonym:

Target: Apoptosis, STAT

PI-273

T12454

Synonym:

Target: Apoptosis, PI4K

NSC 15364

T3572

Synonym: 1,3-Bis(4-aminophenyl)urea,NSC15364

Target: Apoptosis, Others, VDAC

Oncrasin-1

T8006

Synonym:

Target: Apoptosis, Raf, Ras

Sodium 4-phenylbutyrate

T1535

Synonym: Sodium Phenylbutyrate,Buphenyl,TriButyrate

Target: Apoptosis, HDAC, Autophagy

Hexylresorcinol

T0314

Synonym: 4-Hexylresorcinol

Target: Apoptosis, Tyrosinase, Antibacterial, Parasite

Epirubicin hydrochloride

T0125

Synonym: Pharmorubicin,4'-epidoxorubicin HCl,Epirubicin HCl,4'-Epidoxorubicin hydrochloride

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase

TCS PrP Inhibitor 13

T23450

Synonym: 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One

Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111

Synonym: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

Target: Wnt/beta-catenin

CAY10404

T8656

Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Target: Apoptosis, Akt, COX

YK-4-279

T2275

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

CD437

T4371

Synonym: AHPN,O-Desmethyl Adapalene,Apoptosis Activator VI

Target: Retinoid Receptor, Autophagy

WYE-354

T6731

Synonym:

Target: Apoptosis, PI3K, mTOR, Autophagy

Adaphostin

T22553

Synonym: 1-Adamantyl 4-((2,5-Dihydroxybenzyl)Amino)Benzoate,NSC 680410

Target: Apoptosis, GSK-3

VER-50589

T2258

Synonym: VER50589

Target: Apoptosis, HSP

SC-236

T8505

Synonym: Sc 236

Target: Apoptosis, COX, PPAR

Droxinostat

T6481

Synonym: NS 41080

Target: Apoptosis, HDAC

DPN

T7644

Synonym: Diarylpropionitrile

Target: Apoptosis, Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Autophagy

Nelarabine

T6603

Synonym: GW 506U78,Nelzarabine,506U78

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

GW 5074

T6525

Synonym: GW5074,Raf1 Kinase Inhibitor I

Target: Apoptosis, Raf

CGP 57380

T6440

Synonym: MNK1 Inhibitor

Target: Apoptosis, MNK

NSC697923

T6611

Synonym: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran

Target: E1/E2/E3 Enzyme

Tetrahydroxyquinone

T0223

Synonym: 4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

PCI-34051

T6325

Synonym: PCI 34051

Target: Apoptosis, HDAC

ICCB-19 hydrochloride

T8931L

Synonym: ICCB-19 HCl（750621-52-4 free base）

Target: Apoptosis, Others, Autophagy, RIP kinase

GSK-J4

T3100

Synonym: GSK J4 HCl

Target: Apoptosis, Histone Demethylase

SCR130

T9150

Synonym: 1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-

Target: Apoptosis, Others, DNA/RNA Synthesis

Indibulin

T15576

Synonym: ZIO 301,D 24851

Target: Apoptosis, Microtubule Associated

LRRK2-IN-1

T2246

Synonym:

Target: Apoptosis, LRRK2, CDK

PDK4-IN-1 hydrochloride

T12412L

Synonym:

Target: Apoptosis, PDK

Apremilast

T2923

Synonym: CC-10004

Target: Apoptosis, TNF, PDE

DCH36_06

T9373

Synonym: (5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Target: Apoptosis, Epigenetic Reader Domain, Histone Acetyltransferase

GSK4112

T5045

Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452

Target: Apoptosis, CDK

NVP-TAE 684

T2251

Synonym: TAE684

Target: Apoptosis, ALK

CVT-11127

T9003

Synonym:

Target: Dehydrogenase

Voreloxin hydrochloride

T22456

Synonym: SNS-595 hydrochloride,Vosaroxin

Target: Apoptosis, Topoisomerase

BI 2536

T6173

Synonym:

Target: Apoptosis, Epigenetic Reader Domain, PLK

SKF-96365 hydrochloride

T2170

Synonym: SKF96365

Target: Apoptosis, Potassium Channel, Calcium Channel, TRP/TRPV Channel, Autophagy

Serdemetan

T2243

Synonym: JNJ-26854165

Target: Apoptosis, Mdm2, E1/E2/E3 Enzyme, p53

Y-27632 dihydrochloride

T1725

Synonym: Y-27632 2HCl

Target: ROCK, Apoptosis

T0901317

T6690

Synonym:

Target: Apoptosis, FXR, Liver X Receptor, ROR

カタログ番号	製品名	別名	ターゲット
T13509	4-Vinylphenol		Apoptosis , Endogenous Metabolite
			Apoptosis , Endogenous Metabolite
T3752	4-Hydroxybenzyl alcohol	4-Methylolphenol,P-Methylolphenol	Apoptosis , Endogenous Metabolite
	4-Hydroxybenzyl alcohol (P-Methylolphenol) exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybe...		Apoptosis , Endogenous Metabolite
TJS0315	4-Methyldaphnetin	7,8-Dihydroxy-4-methylcoumarin,DHMC	Apoptosis , Lipoxygenase
	4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydr...		Apoptosis , Lipoxygenase
T1297	Eugenol	4-Allylguaiacol,Allylguaiacol,4-Allyl-2-methoxyphenol,Eugenic acid	Apoptosis , Ferroptosis , Reactive Oxygen Species , Antibacterial , Parasite
	Eugenol (Allylguaiacol) is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immunity.
T5557	Propylparaben	Propyl 4-hydroxybenzoate,Propyl parahydroxybenzoate	Apoptosis , Endogenous Metabolite , Antibacterial
	Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agent		Apoptosis , Endogenous Metabolite , Antibacterial
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
T3733	(E)-Methyl 4-coumarate	Methyl trans-p-Coumarat,OMpCA,Methyl 4-hydroxycinnamate	Apoptosis , Others , Antibacterial
	(E)-Methyl 4-coumarate (OMpCA) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of methyl 3-phenylprop-2-enoate.		Apoptosis , Others , Antibacterial
T5728	OsMundacetone	4-(3,4-Dihydroxyphenyl)-3-buten-2-one	Apoptosis , Reactive Oxygen Species
	OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.		Apoptosis , Reactive Oxygen Species
T3981	Acacetin	4'-Methoxyapigenin,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin	Apoptosis , IAP , COX , Autophagy
	Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models.		Apoptosis , IAP , COX , Autophagy
T8296	5,7,4'-Trimethoxyflavone	4',5,7-Trimethoxyflavone	Apoptosis , PARP , Caspase
	5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.		Apoptosis , PARP , Caspase
T2860	Vanillyl Alcohol	4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol	Apoptosis , Others
	Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit ...		Apoptosis , Others
T6S0735	Flavokawain B	Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone	Apoptosis , Others
	1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in...		Apoptosis , Others
T2S0820	Karanjin		Apoptosis , AMPK
	Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arre...		Apoptosis , AMPK
TN1727	Helichrysetin		Apoptosis , HIV Protease
	Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.		Apoptosis , HIV Protease
T2S1907	Coniferaldehyde	Ferulaldehyde,Ferulyl aldehyde,4-HYDROXY-3-METHOXYCINNAMALDEHYDE,Coniferyl aldehyde	Apoptosis , Antioxidant
	Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3. It has a role as an antifungal agent and ...		Apoptosis , Antioxidant
T2570	Vitamin K4	Kapilin,Menadiol Diacetate,acetomenaphthone	Apoptosis , Endogenous Metabolite
	Vitamin K4 (Menadiol Diacetate) is a vitamin medicine for the treatment of blood coagulation disorders that caused by the lack of VK4.		Apoptosis , Endogenous Metabolite
T5715	(E)-Flavokawain A	FLAVOKAVAIN A(P)	Apoptosis , P450
	(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.		Apoptosis , P450
T6S1688	(1E,6E)-Bis(demethoxy)curcumin	Curcumin III,Didemethoxycurcumin,BDMC	Apoptosis , Others , Autophagy
	(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.		Apoptosis , Others , Autophagy
T1511	Daunorubicin hydrochloride	Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin	Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
	Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
TN2211	Silybin B	Silibinin B	Apoptosis , Beta Amyloid , Bcr-Abl
	Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with free radical scavenging activity of 1, 1-dipheny...		Apoptosis , Beta Amyloid , Bcr-Abl
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T2P2923	Stearic acid	Isostearic acid,Octadecanoic acid,Cetylacetic acid	Phosphatase , Endogenous Metabolite
	1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have...		Phosphatase , Endogenous Metabolite
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T27305	Fascaplysin chloride	NSC622398,NSC 622398,Fascaplysin,NSC-622398
	Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 μM). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human ...
T16381	Okadaic acid		Others
	Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted fr...		Others
T14121	Actinonin	(-)-Actinonin	Aminopeptidase
			Aminopeptidase
T35577	Phosphatidylserines (bovine)
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...

天然物製品

4-Vinylphenol

T13509

Synonym:

Target: Apoptosis, Endogenous Metabolite

4-Hydroxybenzyl alcohol

T3752

Synonym: 4-Methylolphenol,P-Methylolphenol

Target: Apoptosis, Endogenous Metabolite

4-Methyldaphnetin

TJS0315

Synonym: 7,8-Dihydroxy-4-methylcoumarin,DHMC

Target: Apoptosis, Lipoxygenase

Eugenol

T1297

Synonym: 4-Allylguaiacol,Allylguaiacol,4-Allyl-2-methoxyphenol,Eugenic acid

Target: Apoptosis, Ferroptosis, Reactive Oxygen Species, Antibacterial, Parasite

Propylparaben

T5557

Synonym: Propyl 4-hydroxybenzoate,Propyl parahydroxybenzoate

Target: Apoptosis, Endogenous Metabolite, Antibacterial

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: MMP, Others

(E)-Methyl 4-coumarate

T3733

Synonym: Methyl trans-p-Coumarat,OMpCA,Methyl 4-hydroxycinnamate

Target: Apoptosis, Others, Antibacterial

OsMundacetone

T5728

Synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Target: Apoptosis, Reactive Oxygen Species

Acacetin

T3981

Synonym: 4'-Methoxyapigenin,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin

Target: Apoptosis, IAP, COX, Autophagy

5,7,4'-Trimethoxyflavone

T8296

Synonym: 4',5,7-Trimethoxyflavone

Target: Apoptosis, PARP, Caspase

Vanillyl Alcohol

T2860

Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol

Target: Apoptosis, Others

Flavokawain B

T6S0735

Synonym: Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone

Target: Apoptosis, Others

Karanjin

T2S0820

Synonym:

Target: Apoptosis, AMPK

Helichrysetin

TN1727

Synonym:

Target: Apoptosis, HIV Protease

Coniferaldehyde

T2S1907

Synonym: Ferulaldehyde,Ferulyl aldehyde,4-HYDROXY-3-METHOXYCINNAMALDEHYDE,Coniferyl aldehyde

Target: Apoptosis, Antioxidant

Vitamin K4

T2570

Synonym: Kapilin,Menadiol Diacetate,acetomenaphthone

Target: Apoptosis, Endogenous Metabolite

(E)-Flavokawain A

T5715

Synonym: FLAVOKAVAIN A(P)

Target: Apoptosis, P450

(1E,6E)-Bis(demethoxy)curcumin

T6S1688

Synonym: Curcumin III,Didemethoxycurcumin,BDMC

Target: Apoptosis, Others, Autophagy

Daunorubicin hydrochloride

T1511

Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy

Silybin B

TN2211

Synonym: Silibinin B

Target: Apoptosis, Beta Amyloid, Bcr-Abl

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Stearic acid

T2P2923

Synonym: Isostearic acid,Octadecanoic acid,Cetylacetic acid

Target: Phosphatase, Endogenous Metabolite

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Fascaplysin chloride

T27305

Synonym: NSC622398,NSC 622398,Fascaplysin,NSC-622398

Synonym: (-)-Actinonin

Target: Aminopeptidase

Phosphatidylserines (bovine)

T35577

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02533	BIRC5 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	BIRC5 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is O70201.
TMPH-00992	BIRC5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	BIRC5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02532	BIRC5 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	BIRC5 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.3 kDa and the accession number is O70201.
TMPY-01216	XIAP Protein, Human, Recombinant (Avi)	Human	E. coli
	XIAP Protein, Human, Recombinant (Avi) is expressed in E. coli expression system with AVI tag. The predicted molecular weight is 29.1 kDa and the accession number is P98170.
TMPY-02922	XIAP Protein, Human, Recombinant (His)	Human	E. coli
	XIAP Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P98170.
TMPJ-00864	VEGF165 Protein, Human, Recombinant	Human	HEK293 Cells
	Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-00749	FGF-2 Protein, Human, Recombinant	Human	E. coli
	FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPK-00823	VEGF165 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-04911	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated	Human,Cynomolgus	HEK293 Cells
	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPK-00423	CD45 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-04754	CASK Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4.
TMPY-01822	PTK9 Protein, Human, Recombinant (His & GST)	Human	E. coli
	PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.
TMPY-04471	APEG1 Protein, Human, Recombinant (His)	Human	E. coli
	Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr...
TMPK-00424	CD45 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPJ-00782	Amyloid Precursor Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and...
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPY-01117	MRAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,...
TMPJ-00233	CD200R1/CRTR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ...
TMPJ-00410	CD45R0 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPY-00380	ANTXR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4.
TMPY-05598	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4.
TMPY-04565	SRPK3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 an...
TMPY-01823	PTK9 Protein, Human, Recombinant	Human	E. coli
	PTK9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29 kDa and the accession number is Q12792-4.
TMPY-00225	CLEC9A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BRU4-4.
TMPJ-01188	CORO6 Protein, Human, Recombinant (His)	Human	E. coli
	Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are...
TMPY-00119	FLT1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
TMPJ-01333	TEM8/ANTXR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothel...
TMPY-04563	CASK Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CASK Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 130 kDa and the accession number is O14936-4.
TMPJ-01256	Caspase-10 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPK-00702	ANTXR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultu...
TMPY-01933	CHI3L2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chondrocyte protein 39 (YKL-39), also known as Chitinase 3-like 2 (CHI3L2), is a secretory protein of articular chondrocytes belonging to the glycosyl hydrolase 18 family. Its highest expression is in chondrocytes, follo...
TMPY-00711	CD45 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4.
TMPK-01356	SIRP alpha V4 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01362	SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...